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EPIDEMIOLOGY Human liver fluke infections are endemic in Eurasia, with at least 680 million people at risk of infection according to estimates published in 2005 (22)

Plant flavonol fisetin belongs to the flavonoid class of polyphenols

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[35] Affected individuals classically present with short stature between 4 and 10 standard deviations below median height, obesity, craniofacial abnormalities, micropenis, low blood sugar, and low serum IGF-1 despite elevated basal serum GH